Readers' Poll: What is the Best Madonna Song of All Time?

Madonna introduces Avicii at Ultra Music Festival in Miami.

Madonna released MDNA, her 12th studio album, earlier this week. It's the latest addition to a discography that extends three decades and includes a truly staggering number of massive era-defining hits.

Our question for you this week is: What is the best Madonna song of all time? You can vote here in the comments, on facebook.com/rollingstone or on Twitter using the #weekendrock hashtag.

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